The effect of crebanine on memory and cognition impairment via the alpha-7 nicotinic acetylcholine receptor.

@article{Rojsanga2012TheEO,
  title={The effect of crebanine on memory and cognition impairment via the alpha-7 nicotinic acetylcholine receptor.},
  author={P. Rojsanga and Chantana Boonyarat and M. Utsintong and {\'A}. Nemecz and J. Yamauchi and T. Talley and A. Olson and Kinzo Matsumoto and O. Vajragupta},
  journal={Life sciences},
  year={2012},
  volume={91 3-4},
  pages={
          107-14
        }
}
AIMS The aims of the present study were to investigate the effect of crebanine on memory and cognition impairment in mice and to elucidate the underlying molecular mechanisms. MAIN METHODS The memory-enhancing effects of crebanine were assessed with a water maze test using scopolamine-induced amnesic mice. The molecular mechanism was explored in silico by docking crebanine against acetylcholine binding proteins (AChBPs) and in vitro with a radioligand competition assay using (±)-[(3)H… Expand
CHOLINERGIC MODULATION OF MEMORY
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Chapter 1 – Alkaloids

References

SHOWING 1-10 OF 33 REFERENCES
Picomolar Amyloid-β Positively Modulates Synaptic Plasticity and Memory in Hippocampus
...
1
2
3
4
...