The effect of continuous positive airway pressure usage on sleepiness in obstructive sleep apnoea: real effects or expectation of benefit?

@article{Crawford2012TheEO,
  title={The effect of continuous positive airway pressure usage on sleepiness in obstructive sleep apnoea: real effects or expectation of benefit?},
  author={Megan R Crawford and Delwyn J. Bartlett and Steven R Coughlin and Craig L. Phillips and Alister M. Neill and Colin A Espie and George C. Dungan and John P H Wilding and Peter M. A. Calverley and Ronald R Grunstein and Nathaniel S Marshall},
  journal={Thorax},
  year={2012},
  volume={67 10},
  pages={920-4}
}
RATIONALE Placebo responses are complex psychobiological phenomena and often involve patient expectation of benefit. With continuous positive airway pressure (CPAP) treatment of obstructive sleep apnoea, greater hours of CPAP use are associated with reduced sleepiness. However, these open-label studies have not controlled for patient expectation of benefit derived from their knowledge of hours of device use. OBJECTIVES To investigate the relative effectiveness of the use of real or placebo… CONTINUE READING
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