The effect of combinations of growth factors on ligament healing.

@article{Letson1994TheEO,
  title={The effect of combinations of growth factors on ligament healing.},
  author={A K Letson and Laurence E. Dahners},
  journal={Clinical orthopaedics and related research},
  year={1994},
  volume={308},
  pages={207-12}
}
Platelet-derived growth factor, basic fibroblast growth factor, and insulin-like growth factor Type 1 have demonstrated chemotactic and mitogenic properties in vitro that could benefit healing ligaments. These growth factors also have demonstrated in vivo effects when used in skin wound-healing models. In a previous study, bFGF and IGF-1, used alone, failed to improve healing. The authors wished to test the hypothesis that platelet-derived growth factor alone or combinations of platelet-derived… CONTINUE READING