The effect of chronic caffeine administration on serum markers of bone mineral metabolism and bone histomorphometry in the rat

@article{Glajchen1988TheEO,
  title={The effect of chronic caffeine administration on serum markers of bone mineral metabolism and bone histomorphometry in the rat},
  author={Neville Glajchen and Firhaad Ismail and Solomon Epstein and Paul S. Jowell and Michael D. Fallon},
  journal={Calcified Tissue International},
  year={1988},
  volume={43},
  pages={277-280}
}
Caffeine has been cited as a risk factor for osteoporosis in humans. In rats, caffeine increases calcium absorption and excretion and raises parathyroid hormone (iPTH) levels. This study investigated the effect of chronic caffeine administration on bone histomorphometry and serum markers of bone mineral metabolism. Twenty-seven male Sprague Dawley rats… CONTINUE READING