The effect of chlorine substitution on the dermal absorption of polychlorinated biphenyls.

@article{Garner1998TheEO,
  title={The effect of chlorine substitution on the dermal absorption of polychlorinated biphenyls.},
  author={Charles E. Garner and Hilary Matthews},
  journal={Toxicology and applied pharmacology},
  year={1998},
  volume={149 2},
  pages={150-8}
}
The fate of selected mono-, di-, tetra-, and hexachlorobiphenyls was investigated following single dermal administration (0.4 mg/kg) to determine the effects of chlorine substitution on the dermal absorption and disposition of polychlorinated biphenyls (PCBs). Single dermal doses of 14C-labeled mono-, di-, tetra-, and hexachlorobiphenyls were administered to 1-cm2 areas on the backs of F-344 male rats. Unabsorbed radioactivity was removed from the dose site either at euthanasia or 48 h postdose… CONTINUE READING

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