The effect of centrally administered neuropeptides on the development of stress-induced gastric ulcers in rats.

@article{Hernndez1983TheEO,
  title={The effect of centrally administered neuropeptides on the development of stress-induced gastric ulcers in rats.},
  author={Daniel E. Hern{\'a}ndez and Charles B. Nemeroff and Roy C. Orlando and Arthur J. Prange},
  journal={Journal of neuroscience research},
  year={1983},
  volume={9 2},
  pages={
          145-57
        }
}
Neurotensin (NT) and bombesin, which are heterogeneously distributed in both brain and gastrointestinal tissue of several mammalian species, inhibit the formation of stress-induced gastric ulcers in rats. Many other endogeneous neuropeptides have also been reported to be present in brain and gastrointestinal tissue. The present study was conducted to evaluate the effect of some of these peptides on the development of cold-restraint stress (CRS)-induced gastric ulcers in rats. In addition, the… CONTINUE READING