The effect of carbon and nitrogen sources on the level of metabolic intermediates in Escherichia coli.

@article{Lowry1971TheEO,
  title={The effect of carbon and nitrogen sources on the level of metabolic intermediates in Escherichia coli.},
  author={Oliver H. Lowry and Jimmy Carter and Jonathan B Ward and Luis Glaser},
  journal={The Journal of biological chemistry},
  year={1971},
  volume={246 21},
  pages={6511-21}
}
The levels of glycolytic intermediates, selected amino acids, and citric acid cycle intermediates have been measured in Escherichia coti in logarithmic growth on a variety of carbon and nitrogen sources, and also after rapid addition of nitrients to cultures. The results have been used to assess the regulatory role of various metabolites in E. coli. Gluconeogenesis is associated with high phosphoenolpyruvate levels and low levels of fructose 1,6-diphosphate, in agreement with the proposed… CONTINUE READING