The effect of camicinal (GSK962040), a motilin agonist, on gastric emptying and glucose absorption in feed-intolerant critically ill patients: a randomized, blinded, placebo-controlled, clinical trial

@inproceedings{Chapman2016TheEO,
  title={The effect of camicinal (GSK962040), a motilin agonist, on gastric emptying and glucose absorption in feed-intolerant critically ill patients: a randomized, blinded, placebo-controlled, clinical trial},
  author={Marianne J. Chapman and Adam M Deane and Stephanie L. O’Connor and Nam Anh Quoc Nguyen and Robert J. L. Fraser and Duncan B Richards and Kimberley E. Hacquoil and Lakshmi S. Vasist Johnson and Matthew E. Barton and George E. Dukes},
  booktitle={Critical care},
  year={2016}
}
BackgroundThe promotility agents currently available to treat gastroparesis and feed intolerance in the critically ill are limited by adverse effects. The aim of this study was to assess the pharmacodynamic effects and pharmacokinetics of single doses of the novel gastric promotility agent motilin agonist camicinal (GSK962040) in critically ill feed-intolerant patients.MethodsA prospective, randomized, double-blind, parallel-group, placebo-controlled, study was performed in mechanically… CONTINUE READING
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