The effect of calorie restriction on acute ethanol-induced oxidative and nitrosative liver injury in rats.

@article{Mladenovi2013TheEO,
  title={The effect of calorie restriction on acute ethanol-induced oxidative and nitrosative liver injury in rats.},
  author={Du{\vs}an R. Mladenovi{\'c} and Milica B Ninkovi{\'c} and Vuk M Aleksi{\'c} and Tamara {\vS}ljivan{\vc}anin and Danijela Vu{\vc}evi{\'c} and Vera N. Todorovi{\'c} and Milena Stankovic and Olivera P. Stanojlovi{\'c} and Tatjana Radosavljevi{\'c}},
  journal={Environmental toxicology and pharmacology},
  year={2013},
  volume={36 2},
  pages={296-302}
}
The aim of our study was to examine the effect of calorie restriction (CR) on oxidative and nitrosative liver injury in rats, induced by acute ethanol intoxication. Male Wistar rats were divided into groups: (1) control; (2) calorie-restricted groups with intake of 60-70% (CR60-70) and 40-50% of daily energy needs (CR40-50); (3) ethanol-treated group (E); (4) calorie-restricted, ethanol-treated groups (E+CR60-70 and E+CR40-50). Ethanol was administered in 5 doses of 2g/kg every 12h, and… CONTINUE READING

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