The effect of caffeine on glucose kinetics in humans--influence of adrenaline.

@article{Battram2005TheEO,
  title={The effect of caffeine on glucose kinetics in humans--influence of adrenaline.},
  author={Danielle S Battram and Terry E. Graham and Erik A Richter and Flemming Dela},
  journal={The Journal of physiology},
  year={2005},
  volume={569 Pt 1},
  pages={347-55}
}
While caffeine impedes insulin-mediated glucose disposal in humans, its effect on endo-genous glucose production (EGP) remains unknown. In addition, the mechanism involved in these effects is unclear, but may be due to the accompanying increase in adrenaline concentration. We studied the effect of caffeine on EGP and glucose infusion rates (GIR), and whether or not adrenaline can account for all of caffeine's effects. Subjects completed three isoglycaemic-hyperinsulinaemic clamps (with 3-[(3)H… CONTINUE READING

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