The effect of caffeine in animal models of learning and memory.

  title={The effect of caffeine in animal models of learning and memory.},
  author={Miriam Elizabeth Mendes Angelucci and Maria Aparecida Barbato Fraz{\~a}o Vital and Carlos Eduardo Ces{\'a}rio and C R Zadusky and Pedro Luiz Rosalen and Claudio Da Cunha},
  journal={European journal of pharmacology},
  volume={373 2-3},
In the present investigation we studied the effect of caffeine on memory task inhibitory avoidance and habituation to a new environment. Caffeine impaired retention scores in mice submitted to inhibitory avoidance and habituation when administered 30 min before training at the doses of 10-30 mg/kg. These effects cannot be explained by state-dependency since the administration of caffeine 30 min before the test session did not reverse the effect of pre-training caffeine administration, but can… CONTINUE READING

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