The effect of caffeic acid phenethyl ester (CAPE) on metabolic enzymes including acetylcholinesterase, butyrylcholinesterase, glutathione S-transferase, lactoperoxidase, and carbonic anhydrase isoenzymes I, II, IX, and XII.

@article{Glin2016TheEO,
  title={The effect of caffeic acid phenethyl ester (CAPE) on metabolic enzymes including acetylcholinesterase, butyrylcholinesterase, glutathione S-transferase, lactoperoxidase, and carbonic anhydrase isoenzymes I, II, IX, and XII.},
  author={İlhami G{\"u}lçin and Andrea Scozzafava and Claudiu T. Supuran and Hulya Akıncıoğlu and Zeynep Koksal and Fikret Turkan and Saleh Hamad Alwasel},
  journal={Journal of enzyme inhibition and medicinal chemistry},
  year={2016},
  volume={31 6},
  pages={
          1095-101
        }
}
Caffeic acid phenethyl ester (CAPE) is an active component of honeybee propolis extracts. Carbonic anhydrases (CAs, EC 4.2.1.1) are widespread and intensively studied metalloenzymes present in higher vertebrates including humans as many diverse isoforms. Acetylcholinesterase (AChE) is responsible for acetyl choline (ACh) hydrolysis and plays a fundamental role in nerve impulse transmission by terminating the action of the ACh neurotransmitter at cholinergic synapses and neuromuscular junctions… CONTINUE READING
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