The effect of budesonide particle mass on drug particle detachment from carrier crystals in adhesive mixtures during inhalation.

@article{Dickhoff2002TheEO,
  title={The effect of budesonide particle mass on drug particle detachment from carrier crystals in adhesive mixtures during inhalation.},
  author={B. Dickhoff and M. Ellison and A. D. de boer and H. Frijlink},
  journal={European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V},
  year={2002},
  volume={54 2},
  pages={
          245-8
        }
}
  • B. Dickhoff, M. Ellison, +1 author H. Frijlink
  • Published 2002
  • Chemistry, Medicine
  • European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V
  • The different fine particle fractions (FPFs) that are obtained, when different dry powder inhalers (DPIs) are used for the same powder formulation at the same flow rate, is the result of different powder de-agglomeration efficiencies for these DPIs. For adhesive mixtures, this is the efficiency with which the kinetic energy of the air flow through the DPI is converted into separation forces that detach drug particles from carrier crystals. We investigated the effect of drug particle diameter… CONTINUE READING
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