The effect of bone marrow transplantation on oxidative stress in X-linked adrenoleukodystrophy.

@article{Rockenbach2012TheEO,
  title={The effect of bone marrow transplantation on oxidative stress in X-linked adrenoleukodystrophy.},
  author={Francieli Juliana Rockenbach and M. P. P. Deon and Daiane P{\'e}res Marchese and Valeria Manfredini and Caroline Paula Mescka and Graziela Schmitt Ribas and Clarissa Troller Habekost and Cl{\'a}udio Galv{\~a}o de Castro and Laura Bannach Jardim and Carmen Regla Vargas},
  journal={Molecular genetics and metabolism},
  year={2012},
  volume={106 2},
  pages={
          231-6
        }
}
Oxidative stress plays an important role in the pathophysiology of neurodegenerative diseases, including X-linked adrenoleukodystrophy (X-ALD). In the present work, we evaluated lipid (malondialdehyde [MDA] content) and protein (sulfhydryl and carbonyl contents) oxidative damage parameters in plasma from X-ALD patients before and after bone marrow transplant (BMT), in order to verify if this treatment is capable to alter the oxidative parameters studied. We also evaluated the plasma… CONTINUE READING
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