The effect of bone marrow depletion on prostaglandin E-producing suppressor macrophages in mouse spleen.

@article{Shibata1985TheEO,
  title={The effect of bone marrow depletion on prostaglandin E-producing suppressor macrophages in mouse spleen.},
  author={Yoshisada Shibata and Alvin Volkman},
  journal={Journal of immunology},
  year={1985},
  volume={135 6},
  pages={3897-904}
}
The i.p. injection of Corynebacterium parvum (CP) into CBA/J mice effected increases in macrophage colony-forming cells (M-CFC) when spleen cells were cultured with L cell culture filtrate as a source of colony-stimulating factor. Significant increases in phagocytic macrophages (M phi) with Fc receptors for IgG2a and IgG2b immune complexes were additionally noted among the spleen cells in these mice. These M phi effectively inhibited Con A-induced lymphocyte proliferation, probably reflecting a… CONTINUE READING
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