The effect of body mass index on overall and disease-free survival in node-positive breast cancer patients treated with docetaxel and doxorubicin-containing adjuvant chemotherapy: the experience of the BIG 02-98 trial

@article{Azambuja2009TheEO,
  title={The effect of body mass index on overall and disease-free survival in node-positive breast cancer patients treated with docetaxel and doxorubicin-containing adjuvant chemotherapy: the experience of the BIG 02-98 trial},
  author={Evandro de Azambuja and Worta J. McCaskill-Stevens and Prudence Francis and Emmanuel Quinaux and John P. A. Crown and Malou Vicente and Rosa Giuliani and B O Nordenskj{\"o}ld and Jorge Guti{\'e}rez and Michael Andersson and Mireia Margel{\'i} Vila and Raimund Jakesz and Jan Demol and Joanna Dewar and Armando Santoro and A{\~n}a Lluch and Steven Olsen and Richard D. Gelber and Angelo Leo and Martine J. Piccart-Gebhart},
  journal={Breast Cancer Research and Treatment},
  year={2009},
  volume={119},
  pages={145-153}
}
Background: Obesity has been shown to be an indicator of poor prognosis for patients with primary breast cancer (BC) regardless of the use of adjuvant systemic therapy. Patients and methods: This is a retrospective analysis of 2,887 node-positive BC patients enrolled in the BIG 02-98 adjuvant study, a randomised phase III trial whose primary objective was to evaluate disease-free survival (DFS) by adding docetaxel to doxorubicin-based chemotherapy. In the current analysis, the effect of body… CONTINUE READING

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References

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Showing 1-10 of 30 references

Breast

  • CG Greenman, CH Jagielski, JJ Griggs
  • CANCER
  • 2008

adjuvant chemotherapy dosing in obese patients : dissemination of information from clinical trials to clinical practice

  • JK Litton, AM Gonzalez-Angulo, CL Warneke
  • 2008

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