The effect of biotin on the formation of different types of E-rosettes by human lymphocytes.


Peripheral blood lymphocytes from healthy human donors were cultured with biotin and concanavalin A (Con A) for varying periods up to 48 h. At the end of incubation, the percentages of total, active, and stable E-rosettes were determined. The percentage of total E-rosettes decreased significantly in the course of time in both cultures with biotin and Con A… (More)


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