The effect of basic fibroblast growth factor on bone regeneration when released from a novel in situ setting tricalcium phosphate cement.

@article{Niedhart2004TheEO,
  title={The effect of basic fibroblast growth factor on bone regeneration when released from a novel in situ setting tricalcium phosphate cement.},
  author={Christopher Niedhart and Uwe Maus and Oliver Miltner and Hans Georg Graeber and Fritz Uwe Niethard and Christian Helge Siebert},
  journal={Journal of biomedical materials research. Part A},
  year={2004},
  volume={69 4},
  pages={
          680-5
        }
}
The osteostimulative effect of the basic fibroblast growth factor is well known, but it is dose dependent, and release kinetic depends on interactions with the used carrier. The aim of our study was to determine the osteostimulative effect of a composite, consisting of an in situ setting tricalcium phosphate cement and basic fibroblast growth factor. A trepanation defect of 1.5 mm in the femur diaphysis of Sprague-Dawley rats was filled with the in situ setting TCP cement combined with 0, 0.25… CONTINUE READING

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