The effect of aspirin on mononuclear cells in aspirin-sensitive asthmatics and control subjects.

@article{Taylor1993TheEO,
  title={The effect of aspirin on mononuclear cells in aspirin-sensitive asthmatics and control subjects.},
  author={M. Lonise Taylor and Geoffrey A. Stewart and Phillip J. Thompson},
  journal={International archives of allergy and immunology},
  year={1993},
  volume={100 2},
  pages={156-63}
}
Three groups, comprising normal subjects (n = 10), aspirin-sensitive asthmatics (ASA+; n = 10) and aspirin-insensitive asthmatics (ASA-; n = 10) were entered into a blinded, parallel group study to asses the modulating effect of aspirin (ASA; 0.0275, 0.275, 1.385, 2.75, 6.9, 13.8 and 27.5 microM) on lymphocyte proliferation in vitro, either alone or in combination with the mitogen, phytohemagglutinin (PHA; 10, 25, 50, 100, 200 and 500 micrograms/ml). The percentage and absolute numbers of CD4… CONTINUE READING

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