The effect of aspirin dosing on platelet function in diabetic and nondiabetic patients: an analysis from the aspirin-induced platelet effect (ASPECT) study.

@article{Dichiara2007TheEO,
  title={The effect of aspirin dosing on platelet function in diabetic and nondiabetic patients: an analysis from the aspirin-induced platelet effect (ASPECT) study.},
  author={Joseph Dichiara and Kevin P. Bliden and Udaya S. Tantry and Miruais S Hamed and Mark J. Antonino and Thomas Su{\'a}rez and Oscar Bailon and Anand Singla and Paul A Gurbel},
  journal={Diabetes},
  year={2007},
  volume={56 12},
  pages={3014-9}
}
OBJECTIVE Diabetic patients may have a higher prevalence of platelet aspirin resistance than nondiabetic patients. Our goal was to analyze platelet aspirin responsiveness to various aspirin doses in diabetic and nondiabetic patients. RESEARCH DESIGN AND METHODS We examined the effect of aspirin (81, 162, and 325 mg/day for 4 weeks each) on platelet aspirin responsiveness in 120 stable outpatients (30 diabetic patients and 90 nondiabetic patients) with coronary artery disease (CAD) using light… CONTINUE READING