The effect of aspartame metabolites on the suckling rat frontal cortex acetylcholinesterase. An in vitro study.

@article{Simintzi2007TheEO,
  title={The effect of aspartame metabolites on the suckling rat frontal cortex acetylcholinesterase. An in vitro study.},
  author={Irene Simintzi and Kleopatra H. Schulpis and Panagoula Angelogianni and Charis Liapi and Stylianos Th Tsakiris},
  journal={Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association},
  year={2007},
  volume={45 12},
  pages={2397-401}
}
UNLABELLED Aspartame (ASP) consumption is suggested to be implicated with muscarinic dysfunction. The aim of this work was to evaluate the effect of ASP and its metabolites on acetylcholinesterase (AChE) activity in rat frontal cortex and pure enzyme. Rat frontal cortex homogenate or pure enzyme AChE (eel E. Electricus) were incubated with ASP and each of… CONTINUE READING