The effect of antipyretic therapy upon outcomes in critically ill patients: a randomized, prospective study.

@article{Schulman2005TheEO,
  title={The effect of antipyretic therapy upon outcomes in critically ill patients: a randomized, prospective study.},
  author={Carl Ivan Schulman and Nicholas Namias and J. G. Doherty and Ronald J Manning and Pamela Stokes Li and Ahmed Elhaddad and David Lasko and Jose D Amortegui and Christopher J. Dy and Lucie B Dlugasch and Gio J. Baracco and Stephen M. Cohn},
  journal={Surgical infections},
  year={2005},
  volume={6 4},
  pages={369-75}
}
BACKGROUND Despite the large body of evidence suggesting a beneficial role of fever in the host response, antipyretic therapy is commonly employed for febrile critically ill patients. Our objective was to evaluate the impact of antipyretic therapy strategies on the outcomes of critically ill patients. METHODS Patients admitted to the Trauma Intensive Care Unit over a nine-month period were eligible for inclusion, except those with traumatic brain injury. Patients were randomized on day three… CONTINUE READING