The effect of antipyretic medications on mortality in critically ill patients with infection: a systematic review and meta-analysis.

@article{Jefferies2011TheEO,
  title={The effect of antipyretic medications on mortality in critically ill patients with infection: a systematic review and meta-analysis.},
  author={Sarah L. Jefferies and Mark Weatherall and Paul D. Young and Sally Jane Eyers and Kyle Gareth Perrin and C Richard W Beasley},
  journal={Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine},
  year={2011},
  volume={13 2},
  pages={
          125-31
        }
}
BACKGROUND Antipyretic medications are widely used in critically ill patients with infection despite evidence supporting a protective, adaptive role of fever. OBJECTIVE To assess the mortality risk of antipyretic medications among critically ill patients with infection. METHODS A systematic search of MEDLINE, Embase, the Cochrane Central Register of Controlled Trials and PubMed was undertaken to identify randomised controlled trials (RCTs) of antipyretic use among critically ill patients… CONTINUE READING

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