The effect of antiepileptic drugs on 5-HT-receptor binding measured by positron emission tomography.

@article{Theodore2006TheEO,
  title={The effect of antiepileptic drugs on 5-HT-receptor binding measured by positron emission tomography.},
  author={William H. Theodore and Giampiero Giovacchini and Robert Bonwetsch and Anto Bagic and Patricia Reeves-Tyer and Peter Herscovitch and Richard E. Carson},
  journal={Epilepsia},
  year={2006},
  volume={47 3},
  pages={499-503}
}
PURPOSE To study the effect of antiepileptic drugs (AEDs) on 5-HT(1A)-receptor binding in patients with temporal lobe epilepsy. 5-HT(1A)-receptor binding, measured by positron emission tomography, is reduced in patients with temporal lobe epilepsy. Antiepileptic drugs may act on the serotonergic system, as shown in animal models, and thus affect receptor… CONTINUE READING