The effect of antibiotic therapy on intrauterine infection-induced preterm parturition in rabbits.

@article{Fidel2003TheEO,
  title={The effect of antibiotic therapy on intrauterine infection-induced preterm parturition in rabbits.},
  author={P I Fidel and Fabio Ghezzi and Roberto Romero and Tinnakorn Chaiworapongsa and Jimmy Espinoza and Jason Cutright and Nelson Wolf and Ricardo Pay{\'a}n Gom{\'e}z},
  journal={The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians},
  year={2003},
  volume={14 1},
  pages={57-64}
}
OBJECTIVE The purpose of this study was to determine whether early antibiotic administration to pregnant rabbits with intrauterine infection could prevent preterm delivery and perinatal mortality. STUDY DESIGN Under hysteroscopic guidance, pregnant rabbits at 70% gestation (21 days) were allocated to three groups: (1) control group, transcervical inoculation of 0.2 ml phosphate-buffered saline (n = 16); (2) infection group, transcervical inoculation of 0.2 ml of 10(5) colony-forming units… CONTINUE READING

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