The effect of anti-resorptive therapies on bone graft healing in an ovariectomized rat spinal arthrodesis model.

@article{Takahata2008TheEO,
  title={The effect of anti-resorptive therapies on bone graft healing in an ovariectomized rat spinal arthrodesis model.},
  author={Masahiko Takahata and Manabu Ito and Yuichiro Abe and Kuniyoshi Abumi and Akio Minami},
  journal={Bone},
  year={2008},
  volume={43 6},
  pages={1057-66}
}
Bone grafting is commonly used to treat skeletal disorders associated with a large bone defect or unstable joint. Spinal arthrodesis surgery, which is the most common application of bone graft, is performed in the elderly and anti-resorptive therapy is sometimes started postoperatively in patients with bone fragility due to osteoporosis, despite insufficient knowledge about the effects of these drugs on bone graft healing. Therefore, we studied the effect of bisphosphonates (BP) and selective… CONTINUE READING
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