The effect of anti-integrin monoclonal antibodies on antigen-induced pulmonary inflammation in allergic rabbits.

@article{Gascoigne2003TheEO,
  title={The effect of anti-integrin monoclonal antibodies on antigen-induced pulmonary inflammation in allergic rabbits.},
  author={Michele H Gascoigne and Karen Holland and Clive P Page and Anthony Shock and Mikella Robinson and Roly Foulkes and Neil Gozzard},
  journal={Pulmonary pharmacology & therapeutics},
  year={2003},
  volume={16 5},
  pages={279-85}
}
The integrin adhesion molecules are involved in the recruitment and activation of inflammatory cells at sites of inflammation in a variety of diseases. In the present study, we have investigated the effects of blocking monoclonal antibodies (mAbs) directed against CD49d (alpha(4) integrin), CD18 (beta(2) integrin) and the alpha sub-units of beta(2) integrin… CONTINUE READING