The effect of anesthetics upon labile phosphates and upon extra- and intracellular lactate, pyruvate and bicarbonate concentrations in the rat brain.

@article{Nilsson1970TheEO,
  title={The effect of anesthetics upon labile phosphates and upon extra- and intracellular lactate, pyruvate and bicarbonate concentrations in the rat brain.},
  author={Lars Nilsson and Bo K. Siesj{\"o}},
  journal={Acta physiologica Scandinavica},
  year={1970},
  volume={80 2},
  pages={
          235-48
        }
}
The effects of volatile anesthetics (nitrous oxide, halothane, diethyl ether and cyclopropane), of Fentanyl, and of barbiturates (thiopentone, phenobarbital and amobarbital) on labile phosphates and on intra- and extracellular lactate, pyruvate and bicarbonate concentrations of brain tissue were investigated in rats, which were immobilized and artificially ventilated so as to give arterial CO2 tensions of 35–40 mm Hg. It was found that the type or the depth of anesthesia did not significantly… CONTINUE READING

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