The effect of anabolic–androgenic steroids on aromatase activity and androgen receptor binding in the rat preoptic area

@article{Roselli1998TheEO,
  title={The effect of anabolic–androgenic steroids on aromatase activity and androgen receptor binding in the rat preoptic area},
  author={Charles E Roselli},
  journal={Brain Research},
  year={1998},
  volume={792},
  pages={271-276}
}
  • C. Roselli
  • Published 11 May 1998
  • Medicine, Biology
  • Brain Research
The level of aromatase in the preoptic area of rats is transcriptionally regulated through a specific androgen-receptor mediated mechanism and can be used as a measure of central androgenic effect. Therefore, several commonly abused anabolic-androgenic steroids (AAS) were tested for their ability to induce aromatase activity in the preoptic area of castrated rats. In addition, we determined the relative binding affinities of these compounds for the androgen receptor, as well as their ability to… Expand
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Brain aromatase in control versus castrated Norway Brown, Sprague-Dawley and Wistar adult rats.
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