The effect of amphetamine on regional cerebral blood flow during cognitive activation in schizophrenia

@inproceedings{Daniel1991TheEO,
  title={The effect of amphetamine on regional cerebral blood flow during cognitive activation in schizophrenia},
  author={D. Daniel and D. Weinberger and D. Jones and J. R. Zigun and R. Coppola and S. Handel and L. Bigelow and T. Goldberg and K. Berman and J. Kleinman},
  booktitle={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={1991}
}
  • D. Daniel, D. Weinberger, +7 authors J. Kleinman
  • Published in
    The Journal of neuroscience…
    1991
  • Psychology, Medicine
  • To explore the role of monoamines on cerebral function during specific prefrontal cognitive activation, we conducted a double-blind placebo- controlled crossover study of the effects of 0.25 mg/kg oral dextroamphetamine on regional cerebral blood flow (rCBF) as determined by 133Xe dynamic single-photon emission-computed tomography (SPECT) during performance of the Wisconsin Card Sorting Test (WCST) and a sensorimotor control task. Ten patients with chronic schizophrenia who had been stabilized… CONTINUE READING
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