The effect of allopurinol and deferrioxamine on rat heart mitochondrial oxidative phosphorylation after normothermic ischemic cardiac arrest and of reperfusion.

Abstract

The electron transport chain of the mitochondria is highly sensitive to myocardial ischemia. As free oxygen radicals take part in the damage that occurred during ischemia, this study was undertaken to determine if allopurinol and deferrioxamine had any beneficial effect on mitochondrial function. Our results showed that perfusion with allopurinol did not… (More)

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@article{Jaarsveld1988TheEO, title={The effect of allopurinol and deferrioxamine on rat heart mitochondrial oxidative phosphorylation after normothermic ischemic cardiac arrest and of reperfusion.}, author={Henretha van Jaarsveld and Andries J. Groenewald and Gavin Potgieter and Stephen Barnard and William JH Vermaak and Helen Barnard}, journal={Research communications in chemical pathology and pharmacology}, year={1988}, volume={62 3}, pages={419-34} }