The effect of aging on the healing of hydroxylapatite implants.

  title={The effect of aging on the healing of hydroxylapatite implants.},
  author={Tatsuo Shirota and Kohsuke Ohno and Koichiro Suzuki and Kenichi Michi},
  journal={Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons},
  volume={51 1},
The purpose of this study was to investigate the effect of aging on the healing process after insertion of a hydroxylapatite (HA) implant into bone. Three groups of eight male Wistar rats, aged 6 weeks (young group), 12 weeks (adult group), and approximately 2 years (old group) were used in this experiment. Two implants were placed into the tibia of each rat. The animals were killed 7, 14, 28, and 56 days after implantation, and 15-microns, hematoxylin-eosin-stained, undecalcified sections were… CONTINUE READING


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