The effect of aging and cardiorespiratory fitness on the lung diffusing capacity response to exercise in healthy humans.

@article{Coffman2017TheEO,
  title={The effect of aging and cardiorespiratory fitness on the lung diffusing capacity response to exercise in healthy humans.},
  author={Kirsten E Coffman and Alex R. Carlson and Andrew D. Miller and Bruce D. Johnson and Bryan J. Taylor},
  journal={Journal of applied physiology},
  year={2017},
  volume={122 6},
  pages={1425-1434}
}
Aging is associated with deterioration in the structure and function of the pulmonary circulation. We characterized the lung diffusing capacity for carbon monoxide (DLCO), alveolar-capillary membrane conductance (DmCO), and pulmonary-capillary blood volume (Vc) response to discontinuous incremental exercise at 25, 50, 75, and 90% of peak work (Wpeak) in four groups: 1) Young [27 ± 3 yr, maximal oxygen consumption (V̇o2max): 110 ± 18% age predicted]; 2) Young Highly Fit (27 ± 3 yr, V̇o2max: 147… CONTINUE READING
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