The effect of ageing on phenotype and function of monocyte-derived Langerhans cells

Abstract

BACKGROUND With increasing age the immune system shows functional decline. In the skin this is associated with an increased incidence of epidermal malignancies and infections. Epidermal Langerhans cells (LCs) act as sentinels of the immune system, recognizing, processing and presenting antigen and inducing T-cell responses. Previous investigations have… (More)
DOI: 10.1111/j.1365-2133.2011.10313.x

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