The effect of age on the induction of tyrosine aminotransferase and tryptophan oxygenase genes by physiological stress.

Expression of the genes coding for tyrosine aminotransferase and tryptophan oxygenase in rats is induced in response to cold stress. We have studied the effect of ageing on this induction. The induction of tyrosine aminotransferase activity in young adult rats (10 months) was about twice that observed with old rats (25 months). This difference between the… CONTINUE READING