The effect of aflatoxins on the incorporation of RNA and protein precursors by isolated hepatocytes.

@article{McIntosh1976TheEO,
  title={The effect of aflatoxins on the incorporation of RNA and protein precursors by isolated hepatocytes.},
  author={P. R. McIntosh and Ivor Howell Evans and Boris Rabin},
  journal={British Journal of Cancer},
  year={1976},
  volume={33},
  pages={440 - 449}
}
Hepatocytes prepared by a simplified enzymatic technique were active in the incorporation of RNA and protein precursors into acid-insoluble material. The incorporation of RNA precursors was very markedly inhibited by low levels of aflatoxin B1 and G1 but not by aflatoxins B2 and G2. The activity of mixed function oxidases (MFO), the drug-metabolizing system… CONTINUE READING