The effect of adalimumab on reducing depression symptoms in patients with moderate to severe psoriasis: a randomized clinical trial.

@article{Menter2010TheEO,
  title={The effect of adalimumab on reducing depression symptoms in patients with moderate to severe psoriasis: a randomized clinical trial.},
  author={Alan Menter and Matthias Augustin and James Edward Signorovitch and Andrew Peng Yu and Eric Qiong Wu and Shiraz R. Gupta and Yanjun Bao and Parvez M. Mulani},
  journal={Journal of the American Academy of Dermatology},
  year={2010},
  volume={62 5},
  pages={
          812-8
        }
}
BACKGROUND Psoriasis is associated with health-related quality-of-life impairment and depression. OBJECTIVE We sought to determine the effect of adalimumab on depression symptoms in patients with psoriasis. METHODS Patients with moderate to severe psoriasis in a randomized, placebo-controlled, double-blind clinical trial were assessed for depression symptoms at baseline and week 12 or early termination (ET) using the Zung Self-rating Depression Scale (ZDS). The effects of adalimumab (40 mg… CONTINUE READING

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Psoriasis, Depression, and Inflammatory Overlap: A Review

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