The effect of acylated polyamine derivatives on polyamine uptake mechanism, cell growth, and polyamine pools in Escherichia coli, and the pursuit of structure/activity relationships.

@article{Karahalios1998TheEO,
  title={The effect of acylated polyamine derivatives on polyamine uptake mechanism, cell growth, and polyamine pools in Escherichia coli, and the pursuit of structure/activity relationships.},
  author={Panagiotis Karahalios and P Mamos and Demitrios H. Vynios and Dionissios A. Papaioannou and Dimitrios L. Kalpaxis},
  journal={European journal of biochemistry},
  year={1998},
  volume={251 3},
  pages={998-1004}
}
Two acetyl analogues of spermidine and five analogues of spermine were used to determine the structural specificity of the polyamine transport system in Escherichia coli by measuring their ability to compete with [14C]putrescine or [14C]spermine for uptake, as well as to inhibit cell growth, and, finally, to affect the intracellular polyamine pools… CONTINUE READING