The effect of acute tryptophan depletion on the BOLD response during performance monitoring and response inhibition in healthy male volunteers

@article{Evers2006TheEO,
  title={The effect of acute tryptophan depletion on the BOLD response during performance monitoring and response inhibition in healthy male volunteers},
  author={Elisabeth A. T. Evers and Frederik M. van der Veen and Jeroen A. van Deursen and Jeroen Schmitt and Nicolaas E P Deutz and Jelle Jolles},
  journal={Psychopharmacology},
  year={2006},
  volume={187},
  pages={200-208}
}
Serotonin (5-HT) was implicated in both clinical and experimental studies in flexible, goal-directed behavior. However, the way in which 5-HT manipulations affect brain activation patterns underlying different subprocesses of cognitive flexibility remains largely unknown. The aim of this study was to investigate the effect of a transient lowering of 5-HT on brain activation during performance monitoring and response inhibition. We used acute tryptophan depletion (ATD), a well-known method to… CONTINUE READING