The effect of acute branched-chain amino acid supplementation on prolonged exercise capacity in a warm environment

@article{Watson2004TheEO,
  title={The effect of acute branched-chain amino acid supplementation on prolonged exercise capacity in a warm environment},
  author={Phillip Watson and Susan M. Shirreffs and Ronald J. Maughan},
  journal={European Journal of Applied Physiology},
  year={2004},
  volume={93},
  pages={306-314}
}
Eight males were recruited to examine the effect of branched-chain amino acid (BCAA) supplementation on exercise capacity in a glycogen-depleted state in a warm environment. Following a exercise and dietary regimen designed to reduce glycogen availability, subjects returned to the laboratory the following morning and remained seated for 2 h, before cycling to volitional exhaustion at 50% V̇O2 peak in a warm environment [30.0 (0.2)°C; mean (SD)]. Four 250 ml aliquots of a 12 g l−1 BCAA solution… 

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References

SHOWING 1-10 OF 51 REFERENCES

Branched-chain amino acids prolong exercise during heat stress in men and women.

TLDR
Results indicate BCAA supplementation prolongs moderate exercise performance in the heat and results indicate psychological data were not influenced by BCAA, and cardiovascular and thermoregulatory data were similar between treatments.

Pre-exercise branched-chain amino acid administration increases endurance performance in rats.

TLDR
It is demonstrated that BCAA administration in rats results in enhanced endurance performance and an increase in blood ammonia during exercise.

Effect of branched-chain amino acid and carbohydrate supplementation on the exercise-induced change in plasma and muscle concentration of amino acids in human subjects.

TLDR
A supply of CHO + BCAA or CHO alone did not affect the exercise-induced increase in the plasma and muscle concentration of aromatic amino acids, indicating that neither BCAA nor CHO influenced the net protein degradation during exercise.

Ingestion of branched‐chain amino acids and tryptophan during sustained exercise in man: failure to affect performance.

TLDR
The data suggest that manipulation of tryptophan supply to the brain either has no additional effect upon serotoninergic activity during prolonged exhaustive exercise or that manipulations of serotoninergic activities functionally does not contribute to mechanisms of fatigue.

Effect of branched-chain amino acids (BCAA), glucose, and glucose plus BCAA on endurance performance in rats.

TLDR
The hypothesis that the effect of BCAA administration on performance could be related to carbohydrate availability during exercise is supported.

Influence of ingesting a solution of branched-chain amino acids on perceived exertion during exercise.

TLDR
The performance in the colour task of Stroops Colour Word Test performed after exercise was improved when BCAAs had been ingested during exercise, compared with the results from the placebo trial.

Effects of carbohydrate feedings on plasma free tryptophan and branched-chain amino acids during prolonged cycling

TLDR
Free Trp and free Trp/BCAA increase progressively during prolonged cycling to fatigue, and changes in plasma free fatty acids probably play a prominent role in these responses.

Effect of initial muscle glycogen levels on protein catabolism during exercise.

  • P. LemonJ. Mullin
  • Medicine, Biology
    Journal of applied physiology: respiratory, environmental and exercise physiology
  • 1980
TLDR
It was concluded that protein is utilized during exercise to a greater extent than is generally assumed and that under certain conditions protein carbon may contribute significantly to exercise caloric cost.

Effects of glucose, glucose plus branched-chain amino acids, or placebo on bike performance over 100 km.

TLDR
It is suggested that neither glucose nor glucose plus glucose plus BCAA ingestion during 100 km of cycling enhance performance in well-trained cyclists.

Low glycogen and branched-chain amino acid ingestion do not impair anaplerosis during exercise in humans.

TLDR
The data suggest that increasing the rate of BCAA oxidation has no measurable effect on muscle TCAI during exercise with low glycogen in humans, and it appears that low resting glycogen per se does not impair the increase in T CAI during moderate exercise.
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