The effect of acute and chronic insulin administration on insulin-like growth factor-I expression in the pituitary-intact and hypophysectomised rat

@article{Salamon1989TheEO,
  title={The effect of acute and chronic insulin administration on insulin-like growth factor-I expression in the pituitary-intact and hypophysectomised rat},
  author={E. Salamon and Jiangming Luo and Liam J. Murphy},
  journal={Diabetologia},
  year={1989},
  volume={32},
  pages={348-353}
}
SummaryAlthough growth hormone is known to be the main regulator of insulin-like growth factor-I, insulin has also been shown to play a role in regulating serum insulin-like growth factor I levels in diabetic animals. While this effect is thought to be due to correction of metabolic perturbations, some studies have suggest that insulin may have a direct effect on growth and/or insulin-like growth factor-I levels. We have examined the effects of acute and chronic insulin administration to non… CONTINUE READING

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