The effect of active hexose correlated compound in modulating cytosine arabinoside-induced hair loss, and 6-mercaptopurine- and methotrexate-induced liver injury in rodents.

@article{Sun2009TheEO,
  title={The effect of active hexose correlated compound in modulating cytosine arabinoside-induced hair loss, and 6-mercaptopurine- and methotrexate-induced liver injury in rodents.},
  author={Buxiang Sun and Koji Wakame and Eri Sato and Hiroshi Nishioka and Okezie I. Aruoma and Hajime Fujii},
  journal={Cancer epidemiology},
  year={2009},
  volume={33 3-4},
  pages={293-9}
}
BACKGROUND Active hexose correlated compound (AHCC) (a mixture of polysaccharides, amino acids, lipids and minerals derived from cultured mycelia of a Basidiomycete mushroom, Lentinula edodes) was used to assess amelioration of alopecia (hair loss) caused by cytosine arabinoside (Ara-C) and modulation of liver injury caused by single doses 6-mercaptopurine (6-MP) plus methotrexate (MTX). METHODS Follicular integrity and hair growth was assessed in male and female SD neonatal rats (8 days old… CONTINUE READING

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