The effect of acetaminophen on the disposition of fenoldopam: competition for sulfation.

@article{Ziemniak1987TheEO,
  title={The effect of acetaminophen on the disposition of fenoldopam: competition for sulfation.},
  author={John A. Ziemniak and N L Allison and Venkata K. Boppana and Jeffrey W Dubb and Robert M. Stote},
  journal={Clinical pharmacology and therapeutics},
  year={1987},
  volume={41 3},
  pages={275-81}
}
Both fenoldopam and acetaminophen undergo conjugation with sulfate in humans. The present study was undertaken to determine if a metabolic interaction exists between these two compounds in humans. Twelve healthy male volunteers participated in a single-dose crossover study with 100 mg fenoldopam (capsule) alone or in combination with 1000 mg acetaminophen… CONTINUE READING