The effect of a diuretic (hydrochlorothiazide) on tear production in humans.

Abstract

The effect of an orally administered diuretic, hydrochlorothiazide, on tear production in 11 normal young human subjects (five men and six women, 18 to 35 years old) was measured in a single-masked study. Schirmer tests with topical anesthetic showed a significant (P = .02) decrease in basal aqueous tear production on days when these subjects were taking… (More)

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