The effect of a combination of copper and hexetidine on plaque formation and the amount of copper retained by dental plaque bacteria.

@article{Grytten1987TheEO,
  title={The effect of a combination of copper and hexetidine on plaque formation and the amount of copper retained by dental plaque bacteria.},
  author={J. Grytten and T. Tollefsen and J. Afseth},
  journal={Acta odontologica Scandinavica},
  year={1987},
  volume={45 6},
  pages={
          429-33
        }
}
  • J. Grytten, T. Tollefsen, J. Afseth
  • Published 1987
  • Medicine
  • Acta odontologica Scandinavica
  • Zn++ in combination with hexetidine exerts a synergistic plaque inhibition. Studies in our laboratory on the mechanism of this effect suggested that Cu++ and hexetidine may have a similar combination effect. This hypothesis was tested in vivo on a human test panel in a double-blind crossover study. The amount of Cu++ retained by plaque bacteria in vitro was also evaluated. Seven volunteers rinsed with the solutions for 1 min twice daily for 5 days. The test solutions were H2O, 1.0 mM CuSO4, 2.0… CONTINUE READING
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