The effect of a clinically practical exercise on levodopa bioavailability and motor response in patients with Parkinson disease.

@article{Lopane2010TheEO,
  title={The effect of a clinically practical exercise on levodopa bioavailability and motor response in patients with Parkinson disease.},
  author={Giovanna Lopane and Manuela Contin and Cesa Lorella Maria Scaglione and F. Medolago Albani and Agostino Baruzzi and Paolo Emilio Martinelli},
  journal={Clinical neuropharmacology},
  year={2010},
  volume={33 5},
  pages={254-6}
}
OBJECTIVE The aim of the study was to investigate the potential effect of short, moderate intensity (≤70% maximum heart rate) cyclette exercise on levodopa (LD)/dopa decarboxylase inhibitor bioavailability and motor response in a subgroup of Parkinson disease (PD) patients presenting a moderate-to-severe delay in fasting morning LD dose absorption and matched motor response. METHODS Ten patients underwent an oral LD instrumental kinetic-dynamic test based on simultaneous serial measurements… CONTINUE READING