The effect of a 10-day space flight on the function, phenotype, and adhesion molecule expression of splenocytes and lymph node lymphocytes.

@article{Grove1995TheEO,
  title={The effect of a 10-day space flight on the function, phenotype, and adhesion molecule expression of splenocytes and lymph node lymphocytes.},
  author={Deborah Grove and Sharon Pishak and Andrea M. Mastro},
  journal={Experimental cell research},
  year={1995},
  volume={219 1},
  pages={102-9}
}
Previous studies have indicated that space flight affects the activation of lymphocytes from humans, monkeys, and rodents. In rats, where lymphocytes from blood, spleen, and lymph nodes have been tested, the accumulated data suggest that the effects of flight on various cells are lymphoid organ-specific. Thus, cells may be affected by variations in trafficking brought about by fluid shifts in microgravity (< 10(-3) g). In this study we examined lymphocyte activation (IL-2 production) as well as… CONTINUE READING
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