The effect of TNF-a antagonists on aortic stiffness and wave reflections: a meta-analysis

@article{Vlachopoulos2017TheEO,
  title={The effect of TNF-a antagonists on aortic stiffness and wave reflections: a meta-analysis},
  author={Charalambos Vlachopoulos and Athanasios Gravos and Georgios Georgiopoulos and Dimitrios G. Terentes-Printzios and Nikolaos S. Ioakeimidis and Dimitrios Vassilopoulos and Kimon Stamatelopoulos and Dimitris Tousoulis},
  journal={Clinical Rheumatology},
  year={2017},
  volume={37},
  pages={515-526}
}
Patients with rheumatoid arthritis (RA) have higher aortic stiffness and cardiovascular risk. Tumor necrosis factor alpha (TNF-a) antagonists reduce inflammation in RA and are indicated for the treatment of patients with severe active rheumatoid disease. However, it is debatable if they have favorable effects on cardiovascular health. The present meta-analysis evaluates the effect of TNF-a antagonists on aortic stiffness and wave reflections, predictors of cardiovascular events and mortality… CONTINUE READING