The effect of RANTES on human sperm chemotaxis.

  title={The effect of RANTES on human sperm chemotaxis.},
  author={Tetsuya Isobe and Hiroyuki Minoura and Keisuke Tanaka and Takashi Shibahara and Naoko Hayashi and Nagayasu Toyoda},
  journal={Human reproduction},
  volume={17 6},
BACKGROUND Follicular fluid (FF) is a powerful stimulator of human sperm hyperactivation and the acrosome reaction. FF causes sperm accumulation by way of chemotaxis. The chemoattractant in FF has not yet been identified in the human. It is well known that some types of chemokine such as RANTES (Regulated on Activation Normal T Expressed and Secreted Chemokine) exist in genital tract fluids (for example, FF, seminal plasma and uterine fluid). Few reports appear to exist concerning the direct… CONTINUE READING