The effect of PMMA-based protein-leaking dialyzers on plasma homocysteine levels.

@article{Galli2003TheEO,
  title={The effect of PMMA-based protein-leaking dialyzers on plasma homocysteine levels.},
  author={Francesco Galli and S. Dott. Benedetti and Umberto Buoncristiani and Marta Piroddi and Carmela Conte and Francesco Canestrari and Emanuela Buoncristiani and Ardesio Floridi},
  journal={Kidney international},
  year={2003},
  volume={64 2},
  pages={
          748-55
        }
}
BACKGROUND Hyperhomocysteinemia is a well-recognized independent risk factor for cardiovascular disease in end-stage renal disease (ESRD) patients. Since homocysteine (Hcy) largely binds to serum proteins (80 to 90%), in this study we investigated the possibility that polymethylmethacrylate (PMMA)-based protein-leaking dialyzers could reduce total plasma Hcy (tHcy) levels in ESRD patients. METHODS Two matched groups of patients (N = 13) showing mild to intermediate hyperhomocysteinemia on… CONTINUE READING
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